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α2β1 integrins spatially restrict Cdc42 activity to stabilise adherens junctions

BACKGROUND: Keratinocytes form the main protective barrier in the skin to separate the underlying tissue from the external environment. In order to maintain this barrier, keratinocytes form robust junctions between neighbouring cells as well as with the underlying extracellular matrix. Cell–cell adh...

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Detalles Bibliográficos
Autores principales: Howden, Jake D., Michael, Magdalene, Hight-Warburton, Willow, Parsons, Maddy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220754/
https://www.ncbi.nlm.nih.gov/pubmed/34158053
http://dx.doi.org/10.1186/s12915-021-01054-9