Cargando…

Pyruvate carboxylase promotes thyroid cancer aggressiveness through fatty acid synthesis

BACKGROUND: Pyruvate carboxylase (PC) is an important anaplerotic enzyme in the tricarboxylic acid cycle (TCA) in cancer cells. Although PC overexpression has been observed in thyroid cancer (TC), the mechanisms involved in the carcinogenic effects of PC are still unclear. METHODS: Bioinformatics an...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Chang, Zhou, Xiang, Pan, Yu, Liu, Yang, Zhang, Yifan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220755/
https://www.ncbi.nlm.nih.gov/pubmed/34158007
http://dx.doi.org/10.1186/s12885-021-08499-9