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Pyruvate carboxylase promotes thyroid cancer aggressiveness through fatty acid synthesis
BACKGROUND: Pyruvate carboxylase (PC) is an important anaplerotic enzyme in the tricarboxylic acid cycle (TCA) in cancer cells. Although PC overexpression has been observed in thyroid cancer (TC), the mechanisms involved in the carcinogenic effects of PC are still unclear. METHODS: Bioinformatics an...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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BioMed Central
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220755/ https://www.ncbi.nlm.nih.gov/pubmed/34158007 http://dx.doi.org/10.1186/s12885-021-08499-9 |