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Individual heterogeneity screened umbilical cord-derived mesenchymal stromal cells with high Treg promotion demonstrate improved recovery of mouse liver fibrosis

BACKGROUND: To investigate the heterogeneities of human umbilical cord mesenchymal stromal cells (HUCMSCs) derived from different donors and their therapeutic variations when applied to mouse liver fibrosis model. METHODS: The characteristics of HUCMSCs derived from multiple donors were comprehensiv...

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Detalles Bibliográficos
Autores principales: Xie, Yuanyuan, Liu, Shuo, Wang, Liudi, Yang, Hui, Tai, Chenxu, Ling, Li, Chen, Libo, Liu, Shanshan, Wang, Bin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220795/
https://www.ncbi.nlm.nih.gov/pubmed/34158112
http://dx.doi.org/10.1186/s13287-021-02430-6