Cargando…

Ceramide Kinase Inhibition Blocks IGF-1-Mediated Survival of Otic Neurosensory Progenitors by Impairing AKT Phosphorylation

Sphingolipids are bioactive lipid components of cell membranes with important signal transduction functions in health and disease. Ceramide is the central building block for sphingolipid biosynthesis and is processed to form structurally and functionally distinct sphingolipids. Ceramide can be phosp...

Descripción completa

Detalles Bibliográficos
Autores principales: León, Yolanda, Magariños, Marta, Varela-Nieto, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220815/
https://www.ncbi.nlm.nih.gov/pubmed/34179008
http://dx.doi.org/10.3389/fcell.2021.678760