Engineered Cytokine Signaling to Improve CAR T Cell Effector Function

Adoptive immunotherapy with T cells genetically modified to express chimeric antigen receptors (CARs) is a promising approach to improve outcomes for cancer patients. While CAR T cell therapy is effective for hematological malignancies, there is a need to improve the efficacy of this therapeutic app...

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Detalles Bibliográficos
Autores principales: Bell, Matthew, Gottschalk, Stephen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220823/
https://www.ncbi.nlm.nih.gov/pubmed/34177932
http://dx.doi.org/10.3389/fimmu.2021.684642

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220823/
https://www.ncbi.nlm.nih.gov/pubmed/34177932
http://dx.doi.org/10.3389/fimmu.2021.684642

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