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Engineered Cytokine Signaling to Improve CAR T Cell Effector Function

Adoptive immunotherapy with T cells genetically modified to express chimeric antigen receptors (CARs) is a promising approach to improve outcomes for cancer patients. While CAR T cell therapy is effective for hematological malignancies, there is a need to improve the efficacy of this therapeutic app...

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Detalles Bibliográficos
Autores principales:	Bell, Matthew, Gottschalk, Stephen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220823/ https://www.ncbi.nlm.nih.gov/pubmed/34177932 http://dx.doi.org/10.3389/fimmu.2021.684642

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