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A convolutional neural network-based regression model to infer the epigenetic crosstalk responsible for CG methylation patterns

BACKGROUND: Epigenetic modifications, including CG methylation (a major form of DNA methylation) and histone modifications, interact with each other to shape their genomic distribution patterns. However, the entire picture of the epigenetic crosstalk regulating the CG methylation pattern is unknown...

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Detalles Bibliográficos
Autores principales: Au Yeung, Wan Kin, Maruyama, Osamu, Sasaki, Hiroyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220828/
https://www.ncbi.nlm.nih.gov/pubmed/34162326
http://dx.doi.org/10.1186/s12859-021-04272-8