Equilibrative nucleoside transporter 1 inhibition rescues energy dysfunction and pathology in a model of tauopathy

Tau pathology is instrumental in the gradual loss of neuronal functions and cognitive decline in tauopathies, including Alzheimer’s disease (AD). Earlier reports showed that adenosine metabolism is abnormal in the brain of AD patients while consequences remained ill-defined. Herein, we aimed at inve...

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Detalles Bibliográficos
Autores principales: Chang, Ching-Pang, Chang, Ya-Gin, Chuang, Pei-Yun, Nguyen, Thi Ngoc Anh, Wu, Kuo-Chen, Chou, Fang-Yi, Cheng, Sin-Jhong, Chen, Hui-Mei, Jin, Lee-Way, Carvalho, Kevin, Huin, Vincent, Buée, Luc, Liao, Yung-Feng, Lin, Chun-Jung, Blum, David, Chern, Yijuang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220833/
https://www.ncbi.nlm.nih.gov/pubmed/34158119
http://dx.doi.org/10.1186/s40478-021-01213-7

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8220833/
https://www.ncbi.nlm.nih.gov/pubmed/34158119
http://dx.doi.org/10.1186/s40478-021-01213-7

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