Quantitative interrogation of protein co-aggregation using multi-color fluorogenic protein aggregation sensors

Co-aggregation of multiple pathogenic proteins is common in neurodegenerative diseases but deconvolution of such biochemical process is challenging. Herein, we developed a dual-color fluorogenic thermal shift assay to simultaneously report on the aggregation of two different proteins and quantitativ...

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Detalles Bibliográficos
Autores principales: Bai, Yulong, Wan, Wang, Huang, Yanan, Jin, Wenhan, Lyu, Haochen, Xia, Qiuxuan, Dong, Xuepeng, Gao, Zhenming, Liu, Yu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2021
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221170/
https://www.ncbi.nlm.nih.gov/pubmed/34221329
http://dx.doi.org/10.1039/d1sc01122g

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221170/
https://www.ncbi.nlm.nih.gov/pubmed/34221329
http://dx.doi.org/10.1039/d1sc01122g

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