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Semisynthetic ‘designer’ p53 sheds light on a phosphorylation–acetylation relay
The tumor suppressor protein p53 is a master regulator of cell fate. The activity of p53 is controlled by a plethora of posttranslational modifications (PTMs). However, despite extensive research, the mechanisms of this regulation are still poorly understood due to a paucity of biochemical studies w...
Autores principales: | Margiola, Sofia, Gerecht, Karola, Müller, Manuel M. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221199/ https://www.ncbi.nlm.nih.gov/pubmed/34221338 http://dx.doi.org/10.1039/d1sc00396h |
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