Lactate dehydrogenase A-dependent aerobic glycolysis promotes natural killer cell anti-viral and anti-tumor function

Natural killer (NK) cells are cytotoxic lymphocytes capable of rapid cytotoxicity, cytokine secretion, and clonal expansion. To sustain such energetically demanding processes, NK cells must increase their metabolic capacity upon activation. However, little is known about the metabolic requirements s...

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Detalles Bibliográficos
Autores principales: Sheppard, Sam, Santosa, Endi K., Lau, Colleen M., Violante, Sara, Giovanelli, Paolo, Kim, Hyunu, Cross, Justin R., Li, Ming O., Sun, Joseph C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221253/
https://www.ncbi.nlm.nih.gov/pubmed/34077737
http://dx.doi.org/10.1016/j.celrep.2021.109210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221253/
https://www.ncbi.nlm.nih.gov/pubmed/34077737
http://dx.doi.org/10.1016/j.celrep.2021.109210

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