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Identification of key transcriptome biomarkers based on a vital gene module associated with pathological changes in Alzheimer’s disease

Dysregulation of transcriptome expression has been reported to play an increasingly significant role in AD. In this study, we firstly identified a vital gene module associated with the accumulation of β-amyloid (Aβ) and phosphorylated tau (p-tau) using the WGCNA method. The vital module, named targe...

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Detalles Bibliográficos
Autores principales: Zhang, Tong, Shen, Yang, Guo, Yiqing, Yao, Junyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221319/
https://www.ncbi.nlm.nih.gov/pubmed/34031265
http://dx.doi.org/10.18632/aging.203017