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Pharmacological targeting of TNS3 with histone deacetylase inhibitor as a therapeutic strategy in esophageal squamous cell carcinoma

Histone acetylation which regulates about 2-10% of genes has been demonstrated to be involved in tumorigenesis of esophageal squamous cell carcinoma (ESCC). In this study, we investigated the treatment response of ESCC to selective histone deacetylase inhibitor (HDACi) LMK-235 and potential biomarke...

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Detalles Bibliográficos
Autores principales: Shi, Yang, Xiang, Zheng, Yang, Huiyu, Khan, Suliman, Li, Ruizhe, Zhou, Siran, Ullah, Saif, Zhang, Jiyu, Liu, Bingrong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221360/
https://www.ncbi.nlm.nih.gov/pubmed/34047714
http://dx.doi.org/10.18632/aging.203091