CaMKII Serine 280 O-GlcNAcylation Links Diabetic Hyperglycemia to Proarrhythmia

RATIONALE: Diabetic hyperglycemia is associated with cardiac dysfunction and increased arrhythmia risk, and CaMKII (calcium/calmodulin-dependent protein kinase II) function has been implicated. CaMKII activity is promoted by both oxidation and O-linked β-N-acetylglucosamine (O-GlcNAc) of known CaMKI...

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Detalles Bibliográficos
Autores principales: Hegyi, Bence, Fasoli, Anna, Ko, Christopher Y., Van, Benjamin W., Alim, Chidera C., Shen, Erin Y., Ciccozzi, Marisa M., Tapa, Srinivas, Ripplinger, Crystal M., Erickson, Jeffrey R., Bossuyt, Julie, Bers, Donald M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221539/
https://www.ncbi.nlm.nih.gov/pubmed/33926209
http://dx.doi.org/10.1161/CIRCRESAHA.120.318402

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221539/
https://www.ncbi.nlm.nih.gov/pubmed/33926209
http://dx.doi.org/10.1161/CIRCRESAHA.120.318402

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