Novel enzymatic cross-linking–based hydrogel nanofilm caging system on pancreatic β cell spheroid for long-term blood glucose regulation

Pancreatic β cell therapy for type 1 diabetes is limited by low cell survival rate owing to physical stress and aggressive host immune response. In this study, we demonstrate a multilayer hydrogel nanofilm caging strategy capable of protecting cells from high shear stress and reducing immune respons...

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Detalles Bibliográficos
Autores principales: Kim, Minji, Kim, Hyunbum, Lee, Young-sun, Lee, Sangjun, Kim, Seong-Eun, Lee, Uk-Jae, Jung, Sungwon, Park, Chung-Gyu, Hong, Jinkee, Doh, Junsang, Lee, Dong Yun, Kim, Byung-Gee, Hwang, Nathaniel S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Research Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221614/
https://www.ncbi.nlm.nih.gov/pubmed/34162541
http://dx.doi.org/10.1126/sciadv.abf7832

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221614/
https://www.ncbi.nlm.nih.gov/pubmed/34162541
http://dx.doi.org/10.1126/sciadv.abf7832

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