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Anti-inflammatory nanoparticles significantly improve muscle function in a murine model of advanced muscular dystrophy

Chronic inflammation contributes to the pathogenesis of all muscular dystrophies. Inflammatory T cells damage muscle, while regulatory T cells (T(regs)) promote regeneration. We hypothesized that providing anti-inflammatory cytokines in dystrophic muscle would promote proregenerative immune phenotyp...

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Detalles Bibliográficos
Autores principales: Raimondo, Theresa M., Mooney, David J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221619/
https://www.ncbi.nlm.nih.gov/pubmed/34162554
http://dx.doi.org/10.1126/sciadv.abh3693