Inclusion of maintenance energy improves the intracellular flux predictions of CHO

Chinese hamster ovary (CHO) cells are the leading platform for the production of biopharmaceuticals with human-like glycosylation. The standard practice for cell line generation relies on trial and error approaches such as adaptive evolution and high-throughput screening, which typically take severa...

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Detalles Bibliográficos
Autores principales: Széliová, Diana, Štor, Jerneja, Thiel, Isabella, Weinguny, Marcus, Hanscho, Michael, Lhota, Gabriele, Borth, Nicole, Zanghellini, Jürgen, Ruckerbauer, David E., Rocha, Isabel
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221792/
https://www.ncbi.nlm.nih.gov/pubmed/34115746
http://dx.doi.org/10.1371/journal.pcbi.1009022

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221792/
https://www.ncbi.nlm.nih.gov/pubmed/34115746
http://dx.doi.org/10.1371/journal.pcbi.1009022

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