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Efficient representations of tumor diversity with paired DNA-RNA aberrations

Cancer cells display massive dysregulation of key regulatory pathways due to now well-catalogued mutations and other DNA-related aberrations. Moreover, enormous heterogeneity has been commonly observed in the identity, frequency and location of these aberrations across individuals with the same canc...

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Detalles Bibliográficos
Autores principales: Ke, Qian, Dinalankara, Wikum, Younes, Laurent, Geman, Donald, Marchionni, Luigi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221796/
https://www.ncbi.nlm.nih.gov/pubmed/34115745
http://dx.doi.org/10.1371/journal.pcbi.1008944