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Efficient representations of tumor diversity with paired DNA-RNA aberrations
Cancer cells display massive dysregulation of key regulatory pathways due to now well-catalogued mutations and other DNA-related aberrations. Moreover, enormous heterogeneity has been commonly observed in the identity, frequency and location of these aberrations across individuals with the same canc...
Autores principales: | Ke, Qian, Dinalankara, Wikum, Younes, Laurent, Geman, Donald, Marchionni, Luigi |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221796/ https://www.ncbi.nlm.nih.gov/pubmed/34115745 http://dx.doi.org/10.1371/journal.pcbi.1008944 |
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