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Protein Phosphatase 4 Promotes Hepatocyte Lipoapoptosis by Regulating RAC1/MLK3/JNK Pathway

Lipotoxicity-induced apoptosis, also referred to as lipoapoptosis, is one of the important initial factors promoting the progression from hepatosteatosis to nonalcoholic steatohepatitis (NASH). Saturated free fatty acids (SFAs), which are increased significantly in NASH, are directly hepatotoxic whi...

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Detalles Bibliográficos
Autores principales: Huang, Xiuqing, Yang, Guang, Zhao, Li, Yuan, Huiping, Chen, Hao, Shen, Tao, Tang, Weiqing, Man, Yong, Ma, Jiarui, Ma, Yanyan, Dou, Lin, Li, Jian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8221892/
https://www.ncbi.nlm.nih.gov/pubmed/34221233
http://dx.doi.org/10.1155/2021/5550498