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Inhibition of miR-99a-5p prevents allergen-driven airway exacerbations without compromising type-2 memory responses in the intestine following helminth infection

Acute exacerbations (AE) of asthma, remain one of the biggest concerns for patients living with asthma. As such, identifying the causes, the molecular mechanisms involved and new therapeutic interventions to prevent AE is a high priority. Immunity to intestinal helminths involves the reactivation of...

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Detalles Bibliográficos
Autores principales: Entwistle, Lewis, Aegerter, Helena, Czieso, Stephanie, Amaniti, Eleni, Guidi, Riccardo, Sesay, Abdul, Nikolov, Nikolay, Chakravaty, Probir, Huynh, Alison, Mills, Jessica, Flanagan, Sean, Hambro, Shannon, Nunez, Victor, Cao, Yi, Clarke, Christine, Martzall, Angela, Leong, Laurie, Wilson, Dennis, Austin, Cary, Wilson, Mark
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group US 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222002/
https://www.ncbi.nlm.nih.gov/pubmed/33846533
http://dx.doi.org/10.1038/s41385-021-00401-x