Cancer testis antigen Cyclin A1 harbors several HLA-A*02:01-restricted T cell epitopes, which are presented and recognized in vivo

Cyclin A1 is a promising antigen for T cell therapy being selectively expressed in high-grade ovarian cancer (OC) and acute myeloid leukemia (AML) stem cells. For adoptive T cell therapy, a single epitope has to be selected, with high affinity to MHC class I and adequate processing and presentation...

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Detalles Bibliográficos
Autores principales: Teck, Anja Tatjana, Urban, Sabrina, Quass, Petra, Nelde, Annika, Schuster, Heiko, Letsch, Anne, Busse, Antonia, Walz, Juliane Sarah, Keilholz, Ulrich, Ochsenreither, Sebastian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222032/
https://www.ncbi.nlm.nih.gov/pubmed/32157447
http://dx.doi.org/10.1007/s00262-020-02519-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222032/
https://www.ncbi.nlm.nih.gov/pubmed/32157447
http://dx.doi.org/10.1007/s00262-020-02519-6

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