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Epistatic interactions of genetic loci associated with age-related macular degeneration

The currently largest genome-wide association study (GWAS) for age-related macular degeneration (AMD) defines disease association with genome-wide significance for 52 independent common and rare genetic variants across 34 chromosomal loci. Overall, these loci contain over 7200 variants and are enric...

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Detalles Bibliográficos
Autores principales: Kiel, Christina, Nebauer, Christoph A., Strunz, Tobias, Stelzl, Simon, Weber, Bernhard H. F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222216/
https://www.ncbi.nlm.nih.gov/pubmed/34162900
http://dx.doi.org/10.1038/s41598-021-92351-4