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Using CRISPR to understand how cancer mutations happen
Somatic mutations in cancer genomes can be caused by many different mutational processes, each of which produce distinctive patterns termed “mutational signatures”. Although cancer researchers can now recognize a large number of mutational signatures, exactly how these patterns arise remains unknown...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Nature Publishing Group UK
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222223/ https://www.ncbi.nlm.nih.gov/pubmed/34162994 http://dx.doi.org/10.1038/s42003-021-02313-9 |