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Using CRISPR to understand how cancer mutations happen

Somatic mutations in cancer genomes can be caused by many different mutational processes, each of which produce distinctive patterns termed “mutational signatures”. Although cancer researchers can now recognize a large number of mutational signatures, exactly how these patterns arise remains unknown...

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Detalles Bibliográficos
Autor principal: Rogers, Eve H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222223/
https://www.ncbi.nlm.nih.gov/pubmed/34162994
http://dx.doi.org/10.1038/s42003-021-02313-9