Notch signaling and efficacy of PD-1/PD-L1 blockade in relapsed small cell lung cancer

Immune checkpoint blockade (ICB) benefits only a small subset of patients with small cell lung cancer (SCLC), yet the mechanisms driving benefit are poorly understood. To identify predictors of clinical benefit to ICB, we performed immunogenomic profiling of tumor samples from patients with relapsed...

Descripción completa

Detalles Bibliográficos
Autores principales: Roper, Nitin, Velez, Moises J., Chiappori, Alberto, Kim, Yoo Sun, Wei, Jun S., Sindiri, Sivasish, Takahashi, Nobuyuki, Mulford, Deborah, Kumar, Suresh, Ylaya, Kris, Trindade, Christopher, Manukyan, Irena, Brown, Anna-Leigh, Trepel, Jane B., Lee, Jung-Min, Hewitt, Stephen, Khan, Javed, Thomas, Anish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222224/
https://www.ncbi.nlm.nih.gov/pubmed/34162872
http://dx.doi.org/10.1038/s41467-021-24164-y

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222224/
https://www.ncbi.nlm.nih.gov/pubmed/34162872
http://dx.doi.org/10.1038/s41467-021-24164-y

Ejemplares similares