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A cell-based in vitro assay for testing of immunological integrity of Tetanus toxoid vaccine antigen

Vaccines containing inactivated toxins confer protection by eliciting a neutralizing antibody response against bacterial toxins such as tetanus and diphtheria. At present, release of tetanus toxoid (TT) and diphtheria toxoid (DT)-containing vaccines relies on in vivo experiments showing the protecti...

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Detalles Bibliográficos
Autores principales: Ticha, Olga, Klemm, Dido, Moos, Lukas, Bekeredjian-Ding, Isabelle
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222253/
https://www.ncbi.nlm.nih.gov/pubmed/34162886
http://dx.doi.org/10.1038/s41541-021-00344-1