ATRX promotes heterochromatin formation to protect cells from G-quadruplex DNA-mediated stress

ATRX is a tumor suppressor that has been associated with protection from DNA replication stress, purportedly through resolution of difficult-to-replicate G-quadruplex (G4) DNA structures. While several studies demonstrate that loss of ATRX sensitizes cells to chemical stabilizers of G4 structures, t...

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Detalles Bibliográficos
Autores principales: Teng, Yu-Ching, Sundaresan, Aishwarya, O’Hara, Ryan, Gant, Vincent U., Li, Minhua, Martire, Sara, Warshaw, Jane N., Basu, Amrita, Banaszynski, Laura A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222256/
https://www.ncbi.nlm.nih.gov/pubmed/34162889
http://dx.doi.org/10.1038/s41467-021-24206-5

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222256/
https://www.ncbi.nlm.nih.gov/pubmed/34162889
http://dx.doi.org/10.1038/s41467-021-24206-5

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