Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome

Cell identity is maintained by activation of cell-specific gene programs, regulated by epigenetic marks, transcription factors and chromatin organization. DNA G-quadruplex (G4)-folded regions in cells were reported to be associated with either increased or decreased transcriptional activity. By G4-C...

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Detalles Bibliográficos
Autores principales: Lago, Sara, Nadai, Matteo, Cernilogar, Filippo M., Kazerani, Maryam, Domíniguez Moreno, Helena, Schotta, Gunnar, Richter, Sara N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222265/
https://www.ncbi.nlm.nih.gov/pubmed/34162892
http://dx.doi.org/10.1038/s41467-021-24198-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222265/
https://www.ncbi.nlm.nih.gov/pubmed/34162892
http://dx.doi.org/10.1038/s41467-021-24198-2

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