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Promoter G-quadruplexes and transcription factors cooperate to shape the cell type-specific transcriptome
Cell identity is maintained by activation of cell-specific gene programs, regulated by epigenetic marks, transcription factors and chromatin organization. DNA G-quadruplex (G4)-folded regions in cells were reported to be associated with either increased or decreased transcriptional activity. By G4-C...
Autores principales: | Lago, Sara, Nadai, Matteo, Cernilogar, Filippo M., Kazerani, Maryam, Domíniguez Moreno, Helena, Schotta, Gunnar, Richter, Sara N. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222265/ https://www.ncbi.nlm.nih.gov/pubmed/34162892 http://dx.doi.org/10.1038/s41467-021-24198-2 |
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