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Genetic engineering of porcine endothelial cell lines for evaluation of human-to-pig xenoreactive immune responses

Xenotransplantation (cross-species transplantation) using genetically-engineered pig organs offers a potential solution to address persistent organ shortage. Current evaluation of porcine genetic modifications is to monitor the nonhuman primate immune response and survival after pig organ xenotransp...

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Detalles Bibliográficos
Autores principales: Li, Ping, Walsh, Julia R., Lopez, Kevin, Isidan, Abdulkadir, Zhang, Wenjun, Chen, Angela M., Goggins, William C., Higgins, Nancy G., Liu, Jianyun, Brutkiewicz, Randy R., Smith, Lester J., Hara, Hidetaka, Cooper, David K. C., Ekser, Burcin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222275/
https://www.ncbi.nlm.nih.gov/pubmed/34162938
http://dx.doi.org/10.1038/s41598-021-92543-y