Validation of an adipose-liver human-on-a-chip model of NAFLD for preclinical therapeutic efficacy evaluation

Nonalcoholic fatty liver disease (NAFLD) is the most common liver disease and strongly correlates with the growing incidence of obesity and type II diabetes. We have developed a human-on-a-chip model composed of human hepatocytes and adipose tissue chambers capable of modeling the metabolic factors...

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Detalles Bibliográficos
Autores principales: Slaughter, Victoria L., Rumsey, John W., Boone, Rachel, Malik, Duaa, Cai, Yunqing, Sriram, Narasimhan Narasimhan, Long, Christopher J., McAleer, Christopher W., Lambert, Stephen, Shuler, Michael L., Hickman, J. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222323/
https://www.ncbi.nlm.nih.gov/pubmed/34162924
http://dx.doi.org/10.1038/s41598-021-92264-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222323/
https://www.ncbi.nlm.nih.gov/pubmed/34162924
http://dx.doi.org/10.1038/s41598-021-92264-2

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