Cargando…
The adaptive landscape of a metallo-enzyme is shaped by environment-dependent epistasis
Enzymes can evolve new catalytic activity when environmental changes present them with novel substrates. Despite this seemingly straightforward relationship, factors other than the direct catalytic target can also impact adaptation. Here, we characterize the catalytic activity of a recently evolved...
| Autores principales: | , , , |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group UK
2021
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222346/ https://www.ncbi.nlm.nih.gov/pubmed/34162839 http://dx.doi.org/10.1038/s41467-021-23943-x |