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Data Processing Thresholds for Abundance and Sparsity and Missed Biological Insights in an Untargeted Chemical Analysis of Blood Specimens for Exposomics

Background: An untargeted chemical analysis of bio-fluids provides semi-quantitative data for thousands of chemicals for expanding our understanding about relationships among metabolic pathways, diseases, phenotypes and exposures. During the processing of mass spectral and chromatography data, vario...

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Detalles Bibliográficos
Autores principales: Barupal, Dinesh Kumar, Baygi, Sadjad Fakouri, Wright, Robert O., Arora, Manish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222544/
https://www.ncbi.nlm.nih.gov/pubmed/34178917
http://dx.doi.org/10.3389/fpubh.2021.653599