SCR7, a potent cancer therapeutic agent and a biochemical inhibitor of nonhomologous DNA end‐joining

BACKGROUND: DNA double‐strand breaks (DSBs) are harmful to the cell as it could lead to genomic instability and cell death when left unrepaired. Homologous recombination and nonhomologous end‐joining (NHEJ) are two major DSB repair pathways, responsible for ensuring genome integrity in mammals. Ther...

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Detalles Bibliográficos
Autores principales: Manjunath, Meghana, Choudhary, Bibha, Raghavan, Sathees C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Reviews
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222562/
https://www.ncbi.nlm.nih.gov/pubmed/33496064
http://dx.doi.org/10.1002/cnr2.1341

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222562/
https://www.ncbi.nlm.nih.gov/pubmed/33496064
http://dx.doi.org/10.1002/cnr2.1341

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