A Novel Mice Model for Studying the Efficacy and IRAEs of Anti-CTLA4 Targeted Immunotherapy

BACKGROUND: Patient-derived orthotopic xenograft (PDOX) is a popular animal model for translational cancer research. Immunotherapy is a promising therapy against glioblastoma (GBM). However, the PDOX model is limited to evaluating immune-related events. Our study aims to establish GBM humanized PDOX...

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Detalles Bibliográficos
Autores principales: Xu, Shengchao, Yan, Xi, Dai, Gan, Luo, Chengke
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222697/
https://www.ncbi.nlm.nih.gov/pubmed/34178691
http://dx.doi.org/10.3389/fonc.2021.692403

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222697/
https://www.ncbi.nlm.nih.gov/pubmed/34178691
http://dx.doi.org/10.3389/fonc.2021.692403

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