Variation of Two S3b Residues in K(V)4.1–4.3 Channels Underlies Their Different Modulations by Spider Toxin κ-LhTx-1

The naturally occurred peptide toxins from animal venoms are valuable pharmacological tools in exploring the structure-function relationships of ion channels. Herein we have identified the peptide toxin κ-LhTx-1 from the venom of spider Pandercetes sp (the Lichen huntsman spider) as a novel selectiv...

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Detalles Bibliográficos
Autores principales: Xiao, Zhen, Zhao, Piao, Wu, Xiangyue, Kong, Xiangjin, Wang, Ruiwen, Liang, Songping, Tang, Cheng, Liu, Zhonghua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222713/
https://www.ncbi.nlm.nih.gov/pubmed/34177600
http://dx.doi.org/10.3389/fphar.2021.692076

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222713/
https://www.ncbi.nlm.nih.gov/pubmed/34177600
http://dx.doi.org/10.3389/fphar.2021.692076

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