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Variation of Two S3b Residues in K(V)4.1–4.3 Channels Underlies Their Different Modulations by Spider Toxin κ-LhTx-1
The naturally occurred peptide toxins from animal venoms are valuable pharmacological tools in exploring the structure-function relationships of ion channels. Herein we have identified the peptide toxin κ-LhTx-1 from the venom of spider Pandercetes sp (the Lichen huntsman spider) as a novel selectiv...
Autores principales: | Xiao, Zhen, Zhao, Piao, Wu, Xiangyue, Kong, Xiangjin, Wang, Ruiwen, Liang, Songping, Tang, Cheng, Liu, Zhonghua |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222713/ https://www.ncbi.nlm.nih.gov/pubmed/34177600 http://dx.doi.org/10.3389/fphar.2021.692076 |
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