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Excessive mechanical stretch-mediated osteoblasts promote the catabolism and apoptosis of chondrocytes via the Wnt/β-catenin signaling pathway

Excessive biomechanical loading is considered an important cause of osteoarthritis. Although the mechanical responses of chondrocytes and osteoblasts have been investigated, their communication during mechanical loading and the underlying molecular mechanisms are not yet fully known. The present stu...

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Detalles Bibliográficos
Autores principales: Song, Cheng-Xian, Liu, Sheng-Yao, Zhu, Wen-Ting, Xu, Shao-Yong, Ni, Guo-Xin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222797/
https://www.ncbi.nlm.nih.gov/pubmed/34165157
http://dx.doi.org/10.3892/mmr.2021.12232