Unexpected Gating Behaviour of an Engineered Potassium Channel Kir

In this study, we investigated the dynamics and functional characteristics of the KirBac3.1 S129R, a mutated bacterial potassium channel for which the inner pore-lining helix (TM2) was engineered so that the bundle crossing is trapped in an open conformation. The structure of this channel has been p...

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Detalles Bibliográficos
Autores principales: Fagnen, Charline, Bannwarth, Ludovic, Zuniga, Dania, Oubella, Iman, De Zorzi, Rita, Forest, Eric, Scala, Rosa, Guilbault, Samuel, Bendahhou, Saïd, Perahia, David, Vénien-Bryan, Catherine
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Molecular Biosciences
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222812/
https://www.ncbi.nlm.nih.gov/pubmed/34179097
http://dx.doi.org/10.3389/fmolb.2021.691901

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222812/
https://www.ncbi.nlm.nih.gov/pubmed/34179097
http://dx.doi.org/10.3389/fmolb.2021.691901

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