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PDGFRα-Signaling Is Dispensable for the Development of the Sinoatrial Node After Its Fate Commitment

Palate-derived growth factor receptor α (Pdgfrα) signaling has been reported to play important roles in the cardiac development. A previous study utilizing Pdgfrα conventional knockout mice reported hypoplasia of the sinus venous myocardium including the sinoatrial node (SAN) accompanied by increase...

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Detalles Bibliográficos
Autores principales: Zheng, Xi, Wang, Fengjiao, Hu, Xiaoxiao, Li, Hua, Guan, Zhen, Zhang, Yanding, Hu, Xuefeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222823/
https://www.ncbi.nlm.nih.gov/pubmed/34178981
http://dx.doi.org/10.3389/fcell.2021.647165