Cargando…

Novel adenosine derivatives against SARS-CoV-2 RNA-dependent RNA polymerase: an in silico perspective

BACKGROUND: SARS-CoV-2 is a newly emerged human coronavirus that severely affected human health and the economy. The viral RNA-dependent RNA polymerase (RdRp) is a crucial protein target to stop virus replication. The adenosine derivative, remdesivir, was authorized for emergency use 10 months ago b...

Descripción completa

Detalles Bibliográficos
Autores principales: Sonousi, Amr, Mahran, Hanan A., Ibrahim, Ibrahim M., Ibrahim, Mohamed N., Elfiky, Abdo A., Elshemey, Wael M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222949/
https://www.ncbi.nlm.nih.gov/pubmed/34165771
http://dx.doi.org/10.1007/s43440-021-00300-9