Cargando…

Novel adenosine derivatives against SARS-CoV-2 RNA-dependent RNA polymerase: an in silico perspective

BACKGROUND: SARS-CoV-2 is a newly emerged human coronavirus that severely affected human health and the economy. The viral RNA-dependent RNA polymerase (RdRp) is a crucial protein target to stop virus replication. The adenosine derivative, remdesivir, was authorized for emergency use 10 months ago b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sonousi, Amr, Mahran, Hanan A., Ibrahim, Ibrahim M., Ibrahim, Mohamed N., Elfiky, Abdo A., Elshemey, Wael M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222949/ https://www.ncbi.nlm.nih.gov/pubmed/34165771 http://dx.doi.org/10.1007/s43440-021-00300-9

Ejemplares similares

Molecular dynamics simulations and MM-GBSA reveal novel guanosine derivatives against SARS-CoV-2 RNA dependent RNA polymerase
por: Elfiky, Abdo A., et al.
Publicado: (2022)

Interference of Chaga mushroom terpenoids with the attachment of SARS-CoV-2; in silico perspective
por: Elshemey, Wael M., et al.
Publicado: (2022)

Host-cell recognition of SARS-CoV-2 spike receptor binding domain from different variants
por: Elfiky, Abdo A, et al.
Publicado: (2022)

Alkaloids and flavonoids from African phytochemicals as potential inhibitors of SARS-Cov-2 RNA-dependent RNA polymerase: an in silico perspective
por: Ogunyemi, Oludare M, et al.
Publicado: (2020)

A possible role for GRP78 in cross vaccination against COVID-19
por: Elfiky, Abdo A., et al.
Publicado: (2021)

Recognition through GRP78 is enhanced in the UK, South African, and Brazilian variants of SARS-CoV-2; An in silico perspective
por: Ibrahim, Ibrahim M., et al.
Publicado: (2021)

SARS-CoV-2 Delta Variant is Recognized Through GRP78 Host-Cell Surface Receptor, In Silico Perspective
por: Elfiky, Abdo A., et al.
Publicado: (2022)

Repurposing antiviral drugs against the human monkeypox virus DNA-dependent RNA polymerase; in silico perspective
por: Abduljalil, Jameel M., et al.
Publicado: (2022)

Host-cell recognition through GRP78 is enhanced in the new UK variant of SARS-CoV-2, in silico
por: Elfiky, Abdo A, et al.
Publicado: (2021)

The anti-HCV, Sofosbuvir, versus the anti-EBOV Remdesivir against SARS-CoV-2 RNA dependent RNA polymerase in silico
por: Elfiky, Abdo A., et al.
Publicado: (2021)

Host-cell recognition through Cs-GRP78 is enhanced in the new Omicron variant of SARS-CoV-2, in silico structural point of view
por: Elfiky, Abdo A, et al.
Publicado: (2022)

IDX-184 is a superior HCV direct-acting antiviral drug: a QSAR study
por: Elfiky, Abdo A., et al.
Publicado: (2016)

Exploration of natural compounds against the human mpox virus DNA-dependent RNA polymerase in silico
por: Abduljalil, Jameel M., et al.
Publicado: (2023)

Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARS-CoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study
por: Elfiky, Abdo A.
Publicado: (2020)

Dual targeting of RdRps of SARS-CoV-2 and the mucormycosis-causing fungus: an in silico perspective
por: Elfiky, Abdo A
Publicado: (2022)

Multidimensional in silico strategy for identification of natural polyphenols-based SARS-CoV-2 main protease (M(pro)) inhibitors to unveil a hope against COVID-19
por: Adem, Şevki, et al.
Publicado: (2022)

Potential antiviral properties of antiplatelet agents against SARS-CoV-2 infection: an in silico perspective
por: Abosheasha, Mohammed A., et al.
Publicado: (2021)

Targeting SARS-CoV-2 endoribonuclease: a structure-based virtual screening supported by in vitro analysis
por: Ibrahim, Ibrahim M., et al.
Publicado: (2022)

Corrigendum to “Ribavirin, Remdesivir, Sofosbuvir, Galidesivir, and Tenofovir against SARSCoV-2 RNA dependent RNA polymerase (RdRp): A molecular docking study” [Life Sci. 253 (2020) 117592]
por: Elfiky, Abdo A.
Publicado: (2020)

Targeting SARS-CoV-2 nonstructural protein 15 endoribonuclease: an in silico perspective
por: Mahmud, Shafi, et al.
Publicado: (2021)

GRP78: A possible relationship of COVID-19 and the mucormycosis; in silico perspective
por: Elgohary, Alaa M., et al.
Publicado: (2021)

Seeking antiviral drugs to inhibit SARS-CoV-2 RNA dependent RNA polymerase: A molecular docking analysis
por: Khater, Ibrahim, et al.
Publicado: (2022)

Identification of SARS-CoV-2 RNA-dependent RNA polymerase inhibitors from the major phytochemicals of Nigella sativa: An in silico approach
por: Mir, Shabir Ahmad, et al.
Publicado: (2022)

Facilitating SARS CoV-2 RNA-Dependent RNA polymerase (RdRp) drug discovery by the aid of HCV NS5B palm subdomain binders: In silico approaches and benchmarking
por: Elghoneimy, Laila K., et al.
Publicado: (2021)

GRP78: A cell's response to stress
por: Ibrahim, Ibrahim M., et al.
Publicado: (2019)

In silico evaluation of potential intervention against SARS-CoV-2 RNA-dependent RNA polymerase
por: Kapoor, Shreya, et al.
Publicado: (2023)

Targeting SARS-CoV-2 RNA-dependent RNA polymerase: An in silico drug repurposing for COVID-19
por: Baby, Krishnaprasad, et al.
Publicado: (2020)

In silico identification of promising inhibitor against RNA-dependent RNA polymerase target of SARS-CoV-2
por: Singh, Pushpendra, et al.
Publicado: (2021)

Drummondin E and Flinderole B are potential inhibitors of RNA-dependent RNA polymerase of SARS-CoV-2: an in silico study
por: Akhtar, Nahid, et al.
Publicado: (2022)

Caffeic acid derivatives (CAFDs) as inhibitors of SARS-CoV-2: CAFDs-based functional foods as a potential alternative approach to combat COVID-19
por: Adem, Şevki, et al.
Publicado: (2021)

Screening of potent drug inhibitors against SARS-CoV-2 RNA polymerase: an in silico approach
por: Singh, Sanjay Kumar, et al.
Publicado: (2021)

COVID-19 spike-host cell receptor GRP78 binding site prediction
por: Ibrahim, Ibrahim M., et al.
Publicado: (2020)

Isolation and In Silico Inhibitory Potential against SARS-CoV-2 RNA Polymerase of the Rare Kaempferol 3-O-(6″-O-acetyl)-Glucoside from Calligonum tetrapterum
por: Suleimen, Yerlan M., et al.
Publicado: (2022)

Potential of turmeric-derived compounds against RNA‐dependent RNA polymerase of SARS‐CoV‐2: An in-silico approach
por: Singh, Rahul, et al.
Publicado: (2021)

In silico analysis of RNA-dependent RNA polymerase of the SARS-CoV-2 and therapeutic potential of existing antiviral drugs
por: Mondal, Sunil Kanti, et al.
Publicado: (2021)

Targeting multiple conformations of SARS-CoV2 Papain-Like Protease for drug repositioning: An in-silico study
por: Ismail, Muhammad I., et al.
Publicado: (2021)

Insight into the Hantaan virus RNA-dependent RNA polymerase inhibition using in-silico approaches
por: Faisal, Shah, et al.
Publicado: (2022)

Assessment of circulating levels of microRNA-326, microRNA-424, and microRNA-511 as biomarkers for hepatocellular carcinoma in Egyptians
por: Youssef, Samar Samir, et al.
Publicado: (2022)

SARS-CoV-2 Spike-Heat Shock Protein A5 (GRP78) Recognition may be Related to the Immersed Human Coronaviruses
por: Elfiky, Abdo A.
Publicado: (2020)

Dynamics: the missing link between structure and function of the viral RNA-dependent RNA polymerase?
por: Cameron, Craig E, et al.
Publicado: (2009)

Cannot write session to /tmp/vufind_sessions/sess_o6f0fbt380liu0khemu1rnnb1o