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Dual inhibition of COVID-19 spike glycoprotein and main protease 3CLpro by Withanone from Withania somnifera

OBJECTIVE: To identify the safe and effective natural inhibitors of spike glycoprotein and main protease 3CLpro using potential natural antiviral compounds which are studied under various animal models and viral cell lines. METHODS: First, compounds were retrieved from the PubChem database and predi...

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Detalles Bibliográficos
Autores principales: Patil, Vishal Shivalingappa, Hupparage, Vrushabh B., Malgi, Ajay P., Deshpande, Sanjay H., Patil, Sathgowda A., Mallapur, Shamanand P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8222985/
https://www.ncbi.nlm.nih.gov/pubmed/34188665
http://dx.doi.org/10.1016/j.chmed.2021.06.002