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A Crystallographic Snapshot of SARS-CoV-2 Main Protease Maturation Process

SARS-CoV-2 is the causative agent of COVID-19. The dimeric form of the viral M(pro) is responsible for the cleavage of the viral polyprotein in 11 sites, including its own N and C-terminus. The lack of structural information for intermediary forms of M(pro) is a setback for the understanding its sel...

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Detalles Bibliográficos
Autores principales: Noske, G.D., Nakamura, A.M., Gawriljuk, V.O., Fernandes, R.S., Lima, G.M.A., Rosa, H.V.D., Pereira, H.D., Zeri, A.C.M., Nascimento, A.F.Z., Freire, M.C.L.C., Fearon, D., Douangamath, A., von Delft, F., Oliva, G., Godoy, A.S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Ltd. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223035/
https://www.ncbi.nlm.nih.gov/pubmed/34174328
http://dx.doi.org/10.1016/j.jmb.2021.167118