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Aggravation of hepatic ischemia-reperfusion injury with increased inflammatory cell infiltration is associated with the TGF-β/Smad3 signaling pathway

Ischemia-reperfusion (IR) injury is a major challenge influencing the outcomes of hepatic transplantation. Transforming growth factor-β (TGF-β) and its downstream gene, SMAD family member 3 (Smad3), have been implicated in the pathogenesis of chronic hepatic injuries, such as hepatic fibrosis. Thus,...

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Detalles Bibliográficos
Autores principales: Li, Haixia, Shen, Xiaoyun, Tong, Yifan, Ji, Tong, Feng, Yan, Tang, Yanping, Mai, Rongyun, Ye, Jiaxiang, Que, Ting, Luo, Xiaoling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: D.A. Spandidos 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223105/
https://www.ncbi.nlm.nih.gov/pubmed/34132369
http://dx.doi.org/10.3892/mmr.2021.12219