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Aggravation of hepatic ischemia-reperfusion injury with increased inflammatory cell infiltration is associated with the TGF-β/Smad3 signaling pathway
Ischemia-reperfusion (IR) injury is a major challenge influencing the outcomes of hepatic transplantation. Transforming growth factor-β (TGF-β) and its downstream gene, SMAD family member 3 (Smad3), have been implicated in the pathogenesis of chronic hepatic injuries, such as hepatic fibrosis. Thus,...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
D.A. Spandidos
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223105/ https://www.ncbi.nlm.nih.gov/pubmed/34132369 http://dx.doi.org/10.3892/mmr.2021.12219 |