Discovery of (  ±)-3-(1 H -pyrazol-1-yl)-6,7-dihydro-5 H -[1,2,4]triazolo[3,4- b ][1,3,4] thiadiazine derivatives with promising in vitro anticoronavirus and antitumoral activity

A new series of ( ±)-(3-(3,5-dimethyl-1H-pyrazol-1-yl)-6-phenyl-6,7-dihydro-5H-[1,2,4]triazolo[3,4-b][1,3,4]thiadiazin-7-yl)(phenyl)methanones were efficiently synthesized starting from 4-amino-5-hydrazinyl-4H-1,2,4-triazole-3-thiol 1, acetyl acetone 2, various aromatic and heterocyclic aldehydes 3...

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Detalles Bibliográficos
Autores principales: Jilloju, Parameshwara Chary, Persoons, Leentje, Kurapati, Sathish Kumar, Schols, Dominique, De Jonghe, Steven, Daelemans, Dirk, Vedula, Rajeswar Rao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223195/
https://www.ncbi.nlm.nih.gov/pubmed/34165689
http://dx.doi.org/10.1007/s11030-021-10258-8

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223195/
https://www.ncbi.nlm.nih.gov/pubmed/34165689
http://dx.doi.org/10.1007/s11030-021-10258-8

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