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Exogenous L-carnitine ameliorates burn-induced cellular and mitochondrial injury of hepatocytes by restoring CPT1 activity

BACKGROUND: Impaired hepatic fatty acid metabolism and persistent mitochondrial dysfunction are phenomena commonly associated with liver failure. Decreased serum levels of L-carnitine, a amino acid derivative involved in fatty-acid and energy metabolism, have been reported in severe burn patients. T...

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Detalles Bibliográficos
Autores principales: Li, Pengtao, Xia, Zhengguo, Kong, Weichang, Wang, Qiong, Zhao, Ziyue, Arnold, Ashley, Xu, Qinglian, Xu, Jiegou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223334/
https://www.ncbi.nlm.nih.gov/pubmed/34167568
http://dx.doi.org/10.1186/s12986-021-00592-x