Cargando…

Exogenous L-carnitine ameliorates burn-induced cellular and mitochondrial injury of hepatocytes by restoring CPT1 activity

BACKGROUND: Impaired hepatic fatty acid metabolism and persistent mitochondrial dysfunction are phenomena commonly associated with liver failure. Decreased serum levels of L-carnitine, a amino acid derivative involved in fatty-acid and energy metabolism, have been reported in severe burn patients. T...

Descripción completa

Detalles Bibliográficos
Autores principales:	Li, Pengtao, Xia, Zhengguo, Kong, Weichang, Wang, Qiong, Zhao, Ziyue, Arnold, Ashley, Xu, Qinglian, Xu, Jiegou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8223334/ https://www.ncbi.nlm.nih.gov/pubmed/34167568 http://dx.doi.org/10.1186/s12986-021-00592-x

Ejemplares similares

Polymorphisms in CPT1B and CPT2 have no significant effect on plasma carnitine levels in Japanese cancer patients
por: Hishida, Asahi, et al.
Publicado: (2019)

Muscle Carnitine Palmitoyltransferase II (CPT II) Deficiency: A Conceptual Approach
por: Joshi, Pushpa Raj, et al.
Publicado: (2020)

Carnitine Palmitoyltransferase II Deficiency (CPT II) Followed By Rhabdomyolysis and Acute Kidney Injury
por: Gjorgjievski, Nikola, et al.
Publicado: (2018)

Normal FGF-21-Serum Levels in Patients with Carnitine Palmitoyltransferase II (CPT II) Deficiency
por: Motlagh Scholle, Leila, et al.
Publicado: (2019)

Identification and Characterization of Carnitine Palmitoyltransferase 1 (cpt 1) Genes in Nile Tilapia, Oreochromis niloticus
por: Bayır, Mehtap, et al.
Publicado: (2020)

Carnitine octanoyltransferase is important for the assimilation of exogenous acetyl-L-carnitine into acetyl-CoA in mammalian cells
por: Hsu, Jake, et al.
Publicado: (2022)

Exogenous L-carnitine Administration Ameliorates the Adverse Effects of Heat Stress on Testicular Hemodynamics, Echotexture, and Total Antioxidant Capacity in Rams
por: El-Sherbiny, Hossam R., et al.
Publicado: (2022)

l‐Carnitine therapy improves right heart dysfunction through Cpt1‐dependent fatty acid oxidation
por: Agrawal, Vineet, et al.
Publicado: (2022)

Myopathic Carnitine Palmitoyltransferase II (CPT II) Deficiency: A Rare Cause of Acute Kidney Injury and Cardiomyopathy
por: Castillo, Efrain, et al.
Publicado: (2023)

IL-37 Ameliorates Renal Fibrosis by Restoring CPT1A-Mediated Fatty Acid Oxidation in Diabetic Kidney Disease
por: Xiong, Li, et al.
Publicado: (2023)

Hepatic β-Oxidation and Regulation of Carnitine Palmitoyltransferase (CPT) I in Blunt Snout Bream Megalobrama amblycephala Fed a High Fat Diet
por: Lu, Kang-Le, et al.
Publicado: (2014)

Carnitine Orotate Complex Ameliorates Insulin Resistance and Hepatic Steatosis Through Carnitine Acetyltransferase Pathway
por: Hong, Jung-Hee, et al.
Publicado: (2021)

Pleural translocation and lesions by pulmonary exposed multi-walled carbon nanotubes
por: Wang, Qiong, et al.
Publicado: (2020)

Carnitine palmitoyl transferase-1A (CPT1A): a new tumor specific target in human breast cancer
por: Pucci, Sabina, et al.
Publicado: (2016)

Three Novel and One Potential Hotspot CPT1A Variants in Chinese Patients With Carnitine Palmitoyltransferase 1A Deficiency
por: Zhang, Weifeng, et al.
Publicado: (2021)

Quantitative proteomics reveals Polygonum perfoliatum L. ameliorates hepatic steatosis by promoting PPARs/CPT1A/CPT2-mediated fatty acid β-oxidation
por: Liu, Guanjie, et al.
Publicado: (2023)

Novel Mutations in the CPT1A Gene Identified in the Patient Presenting Jaundice as the First Manifestation of Carnitine Palmitoyltransferase 1A Deficiency
por: Choi, Jong Sub, et al.
Publicado: (2016)

Detection of Early Onset Carnitine Palmitoyltransferase II Deficiency by Newborn Screening: Should CPT II Deficiency Be a Primary Disease Target?
por: Mador-House, Rachel, et al.
Publicado: (2021)

Knockdown of carnitine palmitoyltransferase I (CPT1) reduces fat body lipid mobilization and resistance to starvation in the insect vector Rhodnius prolixus
por: De Paula, Iron F., et al.
Publicado: (2023)

Hypoxic mesenchymal stem cell-derived extracellular vesicles ameliorate renal fibrosis after ischemia–reperfusion injure by restoring CPT1A mediated fatty acid oxidation
por: Gao, Zhumei, et al.
Publicado: (2022)

Function of hepatocyte spheroids in bioactive microcapsules is enhanced by endogenous and exogenous hepatocyte growth factor
por: Gwon, Kihak, et al.
Publicado: (2023)

Simultaneously targeting SOAT1 and CPT1A ameliorates hepatocellular carcinoma by disrupting lipid homeostasis
por: Ren, Meiling, et al.
Publicado: (2021)

Amelioration of popolysaccharide-induced sepsis in rats by free and esterified carnitine
por: Gallo, Linda L., et al.
Publicado: (1993)

l-carnitine alleviates synovitis in knee osteoarthritis by regulating lipid accumulation and mitochondrial function through the AMPK-ACC-CPT1 signaling pathway
por: Liao, Taiyang, et al.
Publicado: (2023)

CPT and Superstring
por: Ellis, John R., et al.
Publicado: (1996)

Surfactant Proteins A/D–CD14 on Alveolar Macrophages Is a Common Pathway Associated With Phagocytosis of Nanomaterials and Cytokine Production
por: Wang, Qiqi, et al.
Publicado: (2021)

Mitigation of statins-induced cytotoxicity and mitochondrial dysfunction by L-carnitine in freshly-isolated rat hepatocytes
por: Abdoli, N., et al.
Publicado: (2015)

Endogenous and exogenous domain markers of the rat hepatocyte plasma membrane
Publicado: (1985)

Doxorubicin Toxicity can be Ameliorated during Antioxidant L-Carnitine Supplementation
por: Alshabanah, Othman A., et al.
Publicado: (2010)

Exogenous L-Carnitine Promotes Plant Growth and Cell Division by Mitigating Genotoxic Damage of Salt Stress
por: Oney-Birol, Signem
Publicado: (2019)

Inflammatory-Dependent Bidirectional Effect of Bile Acids on NLRP3 Inflammasome and Its Role in Ameliorating CPT-11-Induced Colitis
por: Liao, Chuyao, et al.
Publicado: (2022)

Burning, but Not Dying: the Failure of Pyroptotic Cell Death in Hepatocytes
por: Guicciardi, Maria Eugenia, et al.
Publicado: (2021)

Oxidation of Hepatic Carnitine Palmitoyl Transferase-I (CPT-I) Impairs Fatty Acid Beta-Oxidation in Rats Fed a Methionine-Choline Deficient Diet
por: Serviddio, Gaetano, et al.
Publicado: (2011)

Carnitine palmitoyltransferase 1 (CPT1) alleviates oxidative stress and apoptosis of hippocampal neuron in response to beta-Amyloid peptide fragment Aβ(25-35)
por: Ding, Yiyun, et al.
Publicado: (2021)

Normal Thermostability of p.Ser113Leu and p.Arg631Cys Variants of Mitochondrial Carnitine Palmitoyltransferase II (CPT II) in Human Muscle Homogenate
por: Joshi, Pushpa Raj, et al.
Publicado: (2022)

CP, T and CPT at CPLEAR
por: Filipcic, Andrej, et al.
Publicado: (2001)

Tests of CPT with CPLEAR
por: Mikuz, M
Publicado: (2000)

Tests of CPT with CPLEAR
por: Adler, R, et al.
Publicado: (1996)

Test of CPT with antiprotons
por: Poth, Helmut
Publicado: (1978)

Cold antihydrogen and CPT
por: Gabrielse, G, et al.
Publicado: (2002)

Cannot write session to /tmp/vufind_sessions/sess_ll8r0j7cct0hkvt7ve2p5ikukc